Where is plasma produced
Along with water, salt, and enzymes, plasma also contains important components. These include antibodies, clotting factors, and the proteins albumin and fibrinogen. When you donate blood, healthcare providers can separate these vital parts from your plasma. These parts can then be concentrated into various products. These products are then used as treatments that can help save the lives of people suffering from burns, shock, trauma, and other medical emergencies. The proteins and antibodies in plasma are also used in therapies for rare chronic conditions.
These include autoimmune disorders and hemophilia. People with these conditions can live long and productive lives because of the treatments. In fact, some health organizations call plasma "the gift of life. If you have a bleeding disorder or an immune deficiency, you probably already know the importance of medical products made from plasma.
They contain high levels of antibodies against certain infections which can help to protect an individual against the disease, but these antibodies only last for a number of weeks. They do not provide long-term immunity. Tetanus immunoglobulin, for example, contains high levels of antibodies against tetanus and can be used to protect a person who has sustained a tetanus-prone wound but has not previously been vaccinated.
In these circumstances, the patient is usually given a tetanus immunoglobulin injection as well as the tetanus vaccine. This provides them immediate protection against tetanus as well as providing protection over the longer term.
So how exactly does donated plasma get turned into a whole variety of medical products? The first step in the fractionation process is testing the plasma for blood-borne viruses. Next, all the frozen plasma donations are put together and thawed out into a big plasma soup. The plasma is then passed through specialised stainless steel cylinders and separated into the various plasma products. Any viruses in the plasma are then inactivated, with each type of plasma product having its own specific viral inactivation steps.
Some of the other manufacturing steps also contribute to the viral safety of the products. Altogether, there are 15 medical products made in Australia using donated plasma. They fall into three main types: immunoglobulins, clotting factors, and albumin. Immunoglobulins are used to treat immune disorders such as primary or acquired immune deficiency. Albumin is used to treat fluid loss or to supplement low albumin levels—for instance, where someone is suffering from shock due to blood loss.
And that injection my Rh negative colleague Amy will need if she has a baby? When it comes to the red stuff, most of us know that getting the wrong type of blood, say, in a transfusion, is not a good thing. But it may be news to you that plasma, too, needs to be compatible with the blood type of the person receiving it.
Who can safely receive my plasma? Blood type Can safely donate to O-. If you have a particular blood type, this means that your red blood cells have certain kinds of antigens on them antigens are sugars and proteins on the surface of our cells.
My blood type is B positive, so my red blood cells have B antigens on them. White blood cells, red blood cells, and platelets are important to body function. But plasma also plays a key role. This fluid carries the blood components throughout the body.
Plasma is the largest part of your blood. When separated from the rest of the blood, plasma is a light yellow liquid. Plasma carries water, salts and enzymes. The main role of plasma is to take nutrients, hormones, and proteins to the parts of the body that need it.
Cells also put their waste products into the plasma. In addition to transporting waste and regulating body temperature, plasma has several other key functions that are carried out by its different components:. Plasma contains two key proteins called albumin and fibrinogen. Albumin is vital for maintaining a balance of fluid, called oncotic pressure, in the blood.
This pressure is what keeps fluid from leaking into areas of the body and skin where less fluid usually collects. For example, people with low albumin levels may have swelling in their hands, feet, and abdomen. Fibrinogen helps to reduce active bleeding, making it an important part of the blood-clotting process. This makes it harder for blood to clot, which can lead to significant blood loss. Plasma contains gamma globulins, a type of immunoglobulin. Immunoglobulins help the body fight off infections.
Electrolytes conduct electricity when dissolved in water, hence their name. Common electrolytes include sodium, potassium, magnesium, and calcium. Each of these electrolytes plays a key role in the body. When people lose a lot of blood, often due to a traumatic accident or surgery, they also lose a lot of plasma. This is why organizations collect plasma in addition to whole blood. There are two ways to donate plasma. The first is by donating whole blood. A laboratory then separates the blood components, including plasma, as needed.
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