How many cyanobacteria are there

Record-setting algal bloom in Lake Erie caused by agricultural and meteorological trends consistent with expected future conditions. Mihali, T. A putative gene cluster from a Lyngbya wollei bloom that encodes paralytic shellfish toxin biosynthesis. Characterization of the gene cluster responsible for cylindrospermopsin biosynthesis. NH- 5. BMC Biochem. Mikami, S. The media coverage and public awareness of environmental issues in Japan.

Miller, M. Evidence for a novel marine harmful algal bloom: cyanotoxin microcystin transfer from land to Sea Otters. Mizuno, C. Algicidal activity of stilbene analogues. Moffitt, M. Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins. Mohamed, Z. Allelopathic activity of the norharmane-producing cyanobacterium Synechocystis aquatilis against cyanobacteria and microalgae.

Molot, L. A novel model for cyanobacteria bloom formation: the critical role of anoxia and ferrous iron. Muenchhoff, J. A novel prokaryotic L-arginine:glycine amidinotransferase is involved in cylindrospermopsin biosynthesis. FEBS J. Murray-Gulde, C. Algicidal effectiveness of clearigate, cutrine-plus, and copper sulfate and margins of safety associated with their use.

Mynderse, J. Antileukemia activity in the Osillatoriaceae : isolation of debromoaplysiatoxin from Lyngbya. Nakagawa, Y. A simple analogue of tumor-promoting aplysiatoxin is an antineoplastic agent rather than a tumor promoter: development of a synthetically accessible protein kinase C activator with bryostatin-like activity.

Nakai, S. Myriophyllum spicatum- Released allelopathic polyphenols inhibiting growth of blue-green algae Microcystis aeruginosa. Anti-cyanobacterial fatty acids released from Myriophyllum spicatum. Hydrobiologia , 71— Namikoshi, M. Simultaneous production of homoanatoxin-a, anatoxin-a, and a new nontoxic 4-hydroxyhomoanatoxin-a by the cyanobacterium Raphidiopsis mediterranea Skuja. Toxicon 42, — Neilan, B. Environmental conditions that influence toxin biosynthesis in cyanobacteria.

Neumann, C. Studies of the comparative in vitro toxicology of the cyanobacterial metabolite deoxycylindrospermopsin. Health 70, — Nonga, H. Possible involvement of microcystins in the unexplained mass mortalities of Lesser Flamingo Phoeniconaias minor Geoffroy at Lake Manyara in Tanzania.

Norris, R. Deoxycylindrospermopsin, an analog of cylindrospermopsin from Cylindrospermopsis raciborskii. Ohta, T. Nodularin, a potent inhibitor of protein phosphatase 1 and 2A, is a new environmental carcinogen in male F rat liver. Ohtani, I. Cylindrospermopsin: a potent hepatotoxin from the blue-green alga Cylindrospermopsis raciborskii. Okano, K. Characteristics of a microcystin-degrading bacterium under alkaline environmental conditions.

The rise of harmful cyanobacteria blooms: the potential roles of eutrophication and climate change. Harmful Algae 14, — Orjala, J. Antillatoxin: an exceptionally ichthyotoxic cyclic lipopeptide from the tropical cyanobacterium Lyngbya majuscula. Paerl, H. Controlling harmful cyanobacterial blooms in a world experiencing anthropogenic and climatic-induced change.

Blooms like it hot. Science , 57— Climate change: a catalyst for global expansion of harmful cyanobacterial blooms. Climate change: links to global expansion of harmful cyanobacteria.

Throwing fuel on the fire: synergistic effects of excessive nitrogen inputs and global warming on harmful algal blooms.

Palmer, J. Slovenia and Greece. Papadimitriou, T. Assessment of microcystin distribution and biomagnifications in tissues of aquatic food web compartments from a shallow lake.

Ecotoxicology 21, — Park, H. Hepatotoxin microcystin and neurotoxin anatoxin-a contained in natural blooms and strains of cyanobacteria from Japanese waters.

Toxins 1, — Park, M. Growth inhibition of unicellular and colonial Microcystis strains Cyanophyceae by compounds isolated from rice Oryza sativa hulls. Paul, V. Persson, K. Detection of nodularin in European flounder Platichthys flesus in the west coast of Sweden: evidence of nodularin mediated oxidative stress.

Harmful Algae 8, — Pilotto, L. Acute skin irritant effects of cyanobacteria blue-green algae in healthy volunteers. Public Health 28, — Posch, T.

Harmful filamentous cyanobacteria favoured by reduced water turnover with lake warming. Change 2, — Pouria, S. Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil. Lancet , 21— Prepas, E. Lime treatment and its effects on the chemistry and biota of hardwater eutrophic lakes. Preussel, K. First report on cylindrospermopsin producing Aphanizomenon flos-aquae Cyanobacteria isolated from two German lakes. Toxicon 47, — Qin, B.

Mechanism and control of lake eutrophication. Chinese Sci. Qiu, D. The restoration of aquatic macrophytes for improving water quality in a hypertrophic shallow lake in Hubei Province. Qiu, T. The profound effects of microcystin on cardiac antioxidant enzymes, mitochondrial function and cardiac toxicity in rat. Toxicology , 86— Raetz, C. Lipopolysaccharide endotoxins. Ramani, A. Biodegradation 23, 35— Rantala, A. Phylogenetic evidence for the early evolution of microcystin synthesis.

Rantala-Ylinen, A. Anatoxin-a synthetase gene cluster of the cyanobacterium Anabaena sp. Rastogi, R. Biotechnological and industrial significance of cyanobacterial secondary metabolites. The cyanotoxin-microcystins: current overview. Reichwaldt, E. Effects of rainfall patterns on toxic cyanobacterial blooms in a changing climate: between simplistic scenarios and complex dynamics. Rinehart, K. Nodularin, microcystin, and the configuration of Adda.

Robinson, T. The Organic Constituents of Higher Plants. Minneapolis, MN: Burgess publishing Co. Rodriguez, I. Reducing dissolved phosphorus loading to the Salton Sea with aluminum sulfate. Hydrobiologia , 37— Rouhiainen, L. Genes coding for hepatotoxic heptapeptides microcystins in the cyanobacterium Anabaena strain Runnegar, M.

The role of glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes. Ruttenberg, K. Dissolved organic phosphorus production during simulated phytoplankton blooms in a coastal upwelling system. Saito, K. Inhibitory substances from Myriophyllum brasiliense on growth of blue-green algae. Saito, T. Detection and sequencing of the microcystin LR-degrading gene, mlrA, from new bacteria isolated from Japanese lakes.

Saker, M. Cattle mortality attributed to the toxic cyanobacterium Cylindrospermopsis raciborskii in an outback region of north Queensland. Sandrini, G. Changes in gene expression, cell physiology and toxicity of the harmful cyanobacterium Microcystis aeruginosa at elevated CO2. Schindler, D. Eutrophication of lakes cannot be controlled by reducing nitrogen input: results of a 37 year whole ecosystem experiment. Schrader, K. Plant Sci. Novel derivatives of 9,anthraquinone are selective algicides against the musty-odor cyanobacterium Oscillatoria perornata.

Evaluation of the natural product SeaKleen for controlling the musty-odor producing cyanobacterium Oscillatoria perornata in catfish ponds. Seifert, M. First evidence for the production of cylindrospermopsin and deoxy-cylindrospermopsin by the freshwater benthic cyanobacterium, Lyngbya wollei Farlow ex Gomont Speziale and Dyck.

Harmful Algae 6, 73— Shao, J. Potential for control of harmful cyanobacterial blooms using biologically derived substances: problems and prospects. Allelopathic mechanism of pyrogallol to Microcystis aeruginosa PCC Cyanobacteria : from views of gene expression and antioxidant system. Chemosphere 75, — Elucidating the toxicity targets of b-ionone on photosynthetic system of Microcystis aeruginosa NIES- Cyanobacteria. Sieroslawska, A. Effects of cylindrospermopsin on a common carp leucocyte cell line.

Sims, J. Hawaii Med. Sivonen, K. Chorus and J. Smith, J. A review of cyanobacterial odorous and bioactive metabolites: impacts and management alternatives in aquaculture. Aquaculture , 5— Smith, V. Eutrophication of freshwater and coastal marine ecosystems- a global problem.

Eutrophication science: where do we go from here? Trends Ecol. Song, K. Effect of nodularin on the expression of glutathione S-transferase placental form and proliferating cell nuclear antigen in N-nitrosodiethylamine initiated hepato-carcinogenesis in the male Fischer rat.

Carcinogenesis 20, — Song, W. Mechanistic study and the influence of oxygen on the photosensitized transformations of microcystins cyanotoxins. Soto-Liebe, K. Reassessment of the toxin profile of Cylindrospermopsis raciborskii T3 and function of putative sulfotransferases in synthesis of sulfated and sulfonated PSP toxins.

Sotton, B. Nodularin and cylindrospermopsin: a review of their effects on fish. Fish Biol. Fisheries 25, 1— Spencer, D. Influence of aquashade on growth, photosynthesis, and phosphorus uptake of microalgae.

Plant Manage. Spoof, L. First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment Finland. Srivastava, A. Monitoring approaches for a toxic cyanobacterial bloom. Stewart, I. Kenneth Heidelberg: Springer , — Recreational and occupational field exposure to freshwater cyanobacteria - A review of anecdotal and case reports, epidemiological studies and the challenges for epidemiologic assessment.

Health Cyanobacterial lipopolysaccharides and human health-A review. Strichartz, G. On the mechanism by which saxitoxin binds to and blocks sodium channels. Stucken, K. The smallest known genomes of multicellular and toxic cyanobacteria: comparison, minimal gene sets for linked traits and the evolutionary implications. Stuken, A. The cylindrospermopsin gene cluster Aphanizomenon sp. Microbiology , — Su, Z. Sueoka, E. Expression of the tumor necrosis factor alpha gene and early response genes by nodularin, a liver tumor promoter in primary cultured rat hepatocytes.

Sukenik, A. Global expansion of toxic and non-toxic cyanobacteria: effect on ecosystem functioning. Taylor, M. Toxic alkaloids in Lyngbya majuscula and related tropical marine cyanobacteria. Harmful Algae 31, 1—8. Terao, K.

Electron-microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green-alga Umezakia natans. Toxicon 32, — Tillett, D. Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC an integrated peptide-polyketide synthetase system. Tomitani, A. The evolutionary diversification of cyanobacteria: molecular phylogenetic and paleontological perspectives.

Torokne, A. Allergenic sensitization, skin and eye irritation effects of freshwater cyanobacteria-experimental evidence. Tsuji, K. Stability of microcystins from cyanobacteria-II. Effect of UV light on decomposition and isomerization. Toxicon 33, — Tyler, A. Strategies for monitoring and managing mass populations of toxic cyanobacteria in recreational waters: a multi-interdisciplinary approach.

Health 8:S Ufelmann, H. Nodularin-triggered apoptosis and hyperphosphorylation of signaling proteins in cultured rat hepatocytes.

In Vitro 29, 16— Van Hullebusch, E. Environmental impact of two successive chemical treatments in a small shallow eutrophied lake, Part II: case of copper sulfate.

Environmental awareness of the permanent inhabitants of towns and villages on the shores of Lake Balaton with special reference to issues related to global climate change. Vepritskii, A. Production of the antibiotic algicide cyanobacterin LU-2 by a filamentous cyanobacterium Nostoc sp. Mikrobiologia 60, 21— Verdier-Pinard, P. Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.

Verspagen, J. Rising CO2 levels will intensify phytoplankton blooms in eutrophic and hypertrophic lakes. Visser, P. Artificial mixing prevents nuisance blooms of the cyanobacterium Microcystis in Lake Niewe Meer. The Netherlands. Wang, G. A mosaic community of macrophytes for the ecological remediation of eutrophic shallow lakes. Wang, J. Watanabe, M. Isolation and identification of homoanatoxin-a from a toxic strain of the cyanobacterium Raphidiopsis meditarranea Skuja isolated from Lake Biwa.

Whitehead, P. A review of the potential impacts of climate change on surface water quality. Wiegand, C. Ecotoxicological effects of selected cyanobacterial secondary metabolites: a short review. Natural photodegradation of the cyanobacterial toxins microcystin and cylindrospermopsin. Wu, M. Structure, synthesis, and biological properties of kalkitoxin, a novel neurotoxin from the marine cyanobacterium Lyngbya majuscula. Wu, Y. Allelopathic control of cyanobacterial blooms by periphyton biofilms.

Xiao, X. A pair of chiral flavonolignans as novel anti-cyanobacterial allelochemicals derived from barley straw Hordeum vulgare : characterization and comparison of their anti-cyanobacterial activities. Xu, H. Pathway for biodegrading microcystin-YR by Sphingopyxis sp. Xu, L. Changes of public environmental awareness in response to the Taihu blue-green algae bloom incident in China.

Yang, F. Isolation and characterization of an algicidal bacterium indigenous to Lake Taihu with a red pigment able to lyse Microcystis aeruginosa. Biodegradation 25, — Yoshizawa, S. Inhibition of protein phosphatases by microcystis and nodularin associated with hepatotoxicity. Yuan, G. In vivo studies on the immunotoxic effects of microcystins on rabbit. Genotoxicity and potential carcinogenicity of cyanobacterial toxins-a review.

Zhang, D. Transfer, distribution and bioaccumulation of microcystins in the aquatic food web in Lake Taihu, China, with potential risks to human health. Zhang, J.

Identification of a new microcystin-degrading bacterium isolated from lake Chaohu. Please click here to see any active alerts. Blue-green algae, more correctly known as cyanobacteria, are frequently found in freshwater systems. They can also be found in estuarine and marine waters in the U. Cyanobacteria are often confused with green algae, because both can produce dense mats that can impede activities like swimming and fishing, and may cause odor problems and oxygen depletion; however, unlike cyanobacteria, green algae are not generally thought to produce toxins.

Some freshwater cyanobacterial blooms or cyanoHABs are able to produce highly potent toxins, known as cyanotoxins. Cyanotoxins are produced and contained within the cyanobacterial cells intracellular. The release of these toxins in an algal bloom into the surrounding water occurs mostly during cell death and lysis i.

However, some cyanobacteria species are capable of releasing toxins extracellular into the water without cell rupture or death. Cyanotoxins can be produced by a wide variety of planktonic cyanobacteria. Some of the most commonly occurring genera are Microcystis, Dolichospermum previously Anabaena , and Planktothrix. Microcystis is the most common bloom-forming genus, and is almost always toxic. Microcystis blooms resemble a greenish, thick, paint-like sometimes granular material that accumulates along shores.

Scums that dry on the shores of lakes may contain high concentrations of microcystin for several months, allowing toxins to dissolve in the water even when the cells are no longer alive or after a recently collapsed bloom. This is a preview of subscription content, access via your institution. Rent this article via DeepDyve. Quantifying the components of underestimation.

Glob Ecol Biogeogr — Article Google Scholar. Curr Biol — Trends Ecol Evol — PubMed Article Google Scholar. J Biosci — Biodivers Conserv — Proc R Soc B — Divers Distrib — Box GEP Some problems of statistics and everyday life. JASA —4. Google Scholar. Nature — Limnology — Springer, New York, pp — Chapter Google Scholar. Global Ecol Biogeogr — Costello MJ, Wilson S, Houlding B Predicting total global species richness using rates of species description and estimates of taxonomic effort.

Syst Biol — Science — Syst Biol first published online April 10, doi: J Phycol — Diamond JM How many unknown species are yet to be discovered? Ecography — Am J Bot — J Coleopts Bull — Gaston KJ Body size and probability of description: the beetle fauna of Britain. Ecol Entomol — Biol J Linn Soc — Curr Sci — Pearson Benjamin Cummings, San Francisco. Guiry MD How many species of algae are there? J Phycol 48 5 — Heino J A macroecological perspective of diversity patterns in the freshwater realm.