What is iui trigger shot

Current research indicates no significant difference in either clinical pregnancy rates or live birth rates when comparing home monitoring of ovulation with OPKs to ultrasound monitoring and HCG triggering. Therefore, the choice is patient specific. Using a trigger shot also takes some of the guesswork out of the timing of an IUI, and may be beneficial if there are potential scheduling conflicts near ovulation such as you or your spouse leaving town on a business trip.

The bottom line is that there is no right or wrong answer, and you should talk to your doctor about what is going to be most beneficial for you. John Gordon, call or click here. To learn more about Southeastern Fertility, including our mission, values and team, click here. Your email address will not be published. The hormone is produced in the body when it recognizes an egg is fertilized.

As a trigger shot, however, hCG acts more like luteinizing hormone LH , which is made in the pituitary gland right before you ovulate. In this case, we administer more than the normal levels of hCG to get your body to release the multiple mature eggs waiting for release in your ovaries. The shots are administered in your skin or muscle, and are typically self-administered.

Your fertility specialist will work closely with you to learn more about how to administer injectable medications as well as tips for minimizing discomfort. Lupron is not an hCG hormone trigger shot. Instead, it uses an agonist drug that stimulates a response in your body using receptors. Severe OHSS can be life-threatening. Talk to your doctor if you have concerns. However, the general usage of Ovidrel is similar regardless of the fertility treatment protocol.

Ovidrel is given as a subcutaneous injection. This is as opposed to intramuscular injection, like progesterone, that needs to be injected into the muscle. Giving yourself the injection even just a few hours off from the prescribed time can cause problems for your treatment cycle.

Place the used Ovidrel syringe into an approved sharps container. Your fertility clinic will provide instructions on what to do. Most women do not experience any significant side effects beyond local discomfort at the injection point. In clinical trials of Ovidrel, one in three women using the medication for IVF treatment experienced at least one adverse effect.

For those using it for ovulation stimulation only like with an IUI cycle , one in four women experienced at least one adverse effect. Some of the more common adverse effects of Ovidrel include abdominal pain, upset stomach, nausea, vomiting, and pain or bruising at the site of injection.

Whenever fertility drugs are used, there is a risk of developing ovarian hyperstimulation syndrome OHSS. OHSS is more often related to the use of gonadotropins along with Ovidrel, than from taking Ovidrel by itself. Still, you should be aware of the possible symptoms. Talk to your doctor if you experience OHSS symptoms or have any questions. Ovulation typically occurs within 24 to 36 hours of an Ovidrel injection. The optimal time is based on when you gave yourself the trigger shot.

Giving the odds of pregnancy success for those using Ovidrel is tricky because success depends on so many factors. For example, if you have a year old IVF patient with a good prognosis using Ovidrel and compare her to a year-old woman having an IUI cycle using Ovidrel, the success rates will vary significantly.

One study published in looked at whether an r-hCG shot Ovidrel improved IUI pregnancy success rates when compared to cycles where they relied on the natural LH surge, used r-hCG, or timed the injection to occur at the same time as the natural LH surge. The researchers found a significant improvement in pregnancy success for cycles that used r-hCG and especially, those that combined an r-hCG injection with the body's LH surge.

The clinical pregnancy rate per cycle was:. Ovidrel is molecularly similar to the hormone hCG, which is the pregnancy hormone that pregnancy tests detect in the urine.

Ideally, you should not take a pregnancy test until 14 days after your trigger shot. This is the best timing for a pregnancy test with or without having used Ovidrel as taking a pregnancy test too early can lead to false negatives. Your cost for Ovidrel will partially depend on whether you have insurance coverage for fertility treatments and which pharmacy you purchase the drug from.

Pregnyl is a brand name of urinary extracted hCG u-hCG. A Cochrane Database study compared possible adverse effects and clinical pregnancy success rates between Ovidrel and Pregnyl.

The study included 18 random control trials, involving almost 3, participants. Navigating the world of trigger shots, particularly knowing if and when to include fertility medications and which ones into your journey toward pregnancy can be confusing and stressful.

Your healthcare provider will be the best resource to decide which fertility medications and treatments will be most effective for you. In many cases, these medications, including Ovidrel, can greatly improve your shot at making a baby—and once you get the hang of the injections and optimal timing, the process may feel less daunting. Get diet and wellness tips to help your kids stay healthy and happy. Library of Medicine. Daily Med - Ovidrel - choriogonadotropin alfa injection, solution.

Cole LA. Biological functions of hCG and hCG-related molecules.